Pizza Box Football is shaped like a pizza box... and it opens up into a head-to-head football strategy game designed to offer all the intensity of real football in every play. Players unfold the game board (the field) and lay it inside the unfolded pizza box. The cards guide the players as they play and show the players which dice to roll.

Players must apply football strategy in order to win (when to run, when to short pass, when to long pass and when to try to fool the other team). The Advanced Game (sold separately) extends the strategy by offering 3 additional plays for the offense (draw, screen pass and play-action) and 3 additional plays for the defense (run blitz, route jump and QB blitz).